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I wanted to write this as an expansion to DC’s comments on why more frequent shots are better for those of you in Europe and Mexico. I figured I would put the science in English so we could understand how its effects apply to the real world.
First off, I want to give a little lesson on esters and how they affect the hormone itself. We have to understand that the longer acting esters have longer carbon chains. For example, Decanoate as we all know, is a long acting ester which has 10 carbons. Acetate on the other hand, a shorter acting ester has only 2 carbons. Now common sense and physics tells us the larger the ester is the more weight it takes up in the compound when mixed with the hormone and put into a solution. For example, it takes 461 mg of a hormone with a propionate ester attached to equal 288mg of the base hormone without an ester. This means the shorter the ester, the more of the actual hormone you will receive on a milligram per milligram basis. This would mean in the real world that higher doses of long acting esters would be required to get the same effective amount of hormone found in the shorter esters attached to the hormones.
1000 mg of hormone A with a Propionate ester only effectively yields 625 mg of raw the hormone
Now we will talk about ester half lives and frequency of injections. First off what is a half life? A half life is one half of the time it takes for the ester to be completely metabolized by the body. It is at this time that it is estimated that hormone attached to the ester is at it’s peak concentrating in its free form in the body.
Approximate Half Lives of Esters
Prop = 4 days
Acetate = 2 days
Enanthate = 4 days
Cyp = 8 days
Decanoate = 10 days
With this said we can see that it takes deca roughly 10 days to reach it’s peak concentration in the body and 20 days to clear it. Well you think by seeing this you can take a shot once a week or even more with no problems. As common sense would tell us the levels of hormone gradually increase in the body until it has reached it’s half life and then begins to decline. With this said we can now see that once a week doses would lead us to peaks and dips in the level of the hormone. Visualize the half life like a curve on a graph when you think of the levels of the hormone in your body. The more frequent the injections are, the more often your body will have stable and peak levels of the hormone present.
With shorter acting esters it becomes easier to control the level of the hormone in the body, not to mention you receive a more effective dose of the hormone. With the shorter esters it is much easier to predict when the hormone is at it’s peak and when to time the injections. We can obviously see the advantage of using shorter acting esters due to these facts.
This a a quote from Anabolics 2004 “Consistent blood levels probably lead to the greatest efficiency of use for the drug and the highest anabolic/androgenic ratio.” So we can see that more frequent injections are much better for gains.
I hope this clears up some things.
First off, I want to give a little lesson on esters and how they affect the hormone itself. We have to understand that the longer acting esters have longer carbon chains. For example, Decanoate as we all know, is a long acting ester which has 10 carbons. Acetate on the other hand, a shorter acting ester has only 2 carbons. Now common sense and physics tells us the larger the ester is the more weight it takes up in the compound when mixed with the hormone and put into a solution. For example, it takes 461 mg of a hormone with a propionate ester attached to equal 288mg of the base hormone without an ester. This means the shorter the ester, the more of the actual hormone you will receive on a milligram per milligram basis. This would mean in the real world that higher doses of long acting esters would be required to get the same effective amount of hormone found in the shorter esters attached to the hormones.
1000 mg of hormone A with a Propionate ester only effectively yields 625 mg of raw the hormone
Now we will talk about ester half lives and frequency of injections. First off what is a half life? A half life is one half of the time it takes for the ester to be completely metabolized by the body. It is at this time that it is estimated that hormone attached to the ester is at it’s peak concentrating in its free form in the body.
Approximate Half Lives of Esters
Prop = 4 days
Acetate = 2 days
Enanthate = 4 days
Cyp = 8 days
Decanoate = 10 days
With this said we can see that it takes deca roughly 10 days to reach it’s peak concentration in the body and 20 days to clear it. Well you think by seeing this you can take a shot once a week or even more with no problems. As common sense would tell us the levels of hormone gradually increase in the body until it has reached it’s half life and then begins to decline. With this said we can now see that once a week doses would lead us to peaks and dips in the level of the hormone. Visualize the half life like a curve on a graph when you think of the levels of the hormone in your body. The more frequent the injections are, the more often your body will have stable and peak levels of the hormone present.
With shorter acting esters it becomes easier to control the level of the hormone in the body, not to mention you receive a more effective dose of the hormone. With the shorter esters it is much easier to predict when the hormone is at it’s peak and when to time the injections. We can obviously see the advantage of using shorter acting esters due to these facts.
This a a quote from Anabolics 2004 “Consistent blood levels probably lead to the greatest efficiency of use for the drug and the highest anabolic/androgenic ratio.” So we can see that more frequent injections are much better for gains.
I hope this clears up some things.
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