HCG for fat loss

[SweatMachine]

125ius of HCG M-F combined with a litttle B12 is actually melting fat off of some men and women Im helping get into shape. This is the same thing these weight loss clinic prescribe to their patients. . It is especially effective on women combined with a good diet and moderate cardio.

I just thought Id post this info, Im in no way endorsing this or suggesting anyone do this.....

[Kidrok (Hop)]

1) what sides do women need to be aware of with hcg?
2) what is the effects of the b12?

[BigWilly]

Anyone know HOW hcg has this effect?

I have heard on one other occasion of someone using HCG precontest...but at a higher dose....more like 500-1000iu/ed (for men).

bump for more info...

[In-Human]

Could you toast your Leydigs even father into remission, would LH and FSH ever come back after that many IUs in a row, HPTA would take even that much longer...

[SweatMachine]

125 units of HCG is VERY VERY low, the high dose HCG is 1000iu per ml.

My Dr. friend is doing this with hundreds of patients, at $45 per week. He is having tremedous results and has been doing this type of weight loss program for over 20yrs.
Im not going to pretend to know the answers to your questions, But I will TRY to find them out for you from the Dr.

My experience with the people I have worked with has beeen 100% positive. ( about 15 people total) The immediate effect is an average of 3-6lbs of water weight the first week or 2. women seem to loss more water weight than the men. But this program has beeen effective on both men and women for fat loss.

Im sure Randy could expand on the actual physiological processes at work here.
I welcome anyone's educated input or opinion on this topic. It's all about learning, huh?
I'll do what I can to get the answers to your questiions.....

[xcelbeyond]

I remember a couple of years ago, dragonfire posted something like this over at the ol' Fina Board. He got a prescription from a doc and he told him that if he used it sub-q, it would aid in fat loss.

xcel

[homonunculus]

Well, I'll take a stab - this is really pretty interesting, actually. I think it *might* have something to do with leptin.

Leptin is a hormone released by adipocytes (fat cells) when they become larger, that in turn signals increased energy expenditure (e.g., activates the sympathetic nervous system) and reduced food intake. It play and important roll in regulating energy balance control, but is not the end-all-be-all, at least in humans. (E.g., some very obese persons have normal leptin levels and normal leptin receptors...)

As such, it makes sense (teleologically) that leptin would also be involved in reproduction and the reproductive hormones (FSH, LH, GnRH, etc.). Having lots of large fat cells indicates a well fed person (mom or dad) and a situation where full-term pregnancy and successful generation and raising of offspring would be favored: lots of food is good. As such

-Full Fat cells --> leptin release --> *REGULATION* of GnRH, LH, FSH release --> testosterone and spermatogenesis in males, fertility and menstrual cycling in women --> copulation, etc...

Thus my guess is that the LH (=HCG) is somehow tricking the body into releasing larger amounts of leptin, which is elevating metabolic rate.

From what I've read (its been a while), it really seems that leptin is just part of the picture, although it most certainly would be helpful in body fat loss. (In rats, leptin administration will literally reduce body fat eventually to <1%, but doesn't seem to be that one-sided in humans.) If you have starving primates that have low leptin levels (low BMR, but high appetites), as well as low levels of HPTA hormones, administering leptin (to mimic a happy, full fat cell) does not restore the HPTA.

So, that's just a guess. Maybe the HCG is stimulating leptin as a regulator of the HPTA, and, since there is a constant influx of exogenous HCG from the injections that obviously is not affected by the endogenous regulatory effects of leptin, there is a chronically elevated leptin level, faster metabolic rate and fat loss.

Regardless, I would wonder about IH's concern, too - I don't know *what* it takes to really "fry" the leydig cells...

Sweaty, are you having people (or at least guys) take arimidex to counter the HCG's action to upregulate aromatase?...

-R

[GetnBigr]

"Regardless, I would wonder about IH's concern, too - I don't know *what* it takes to really "fry" the leydig cells..."

That makes me wonder if cycling HCG on and off in a similar fashion as one would cycle CLEN and thermos would help keep one from "frying" leydig cells.......

[Bellina]

Bump for more info on female usage and sides.

[SuperSport]

This is a great thread! Props to Sweat for starting it, and Randy the encyclopedia for explaining it, lol.

[Massive G]

Hmmmmmmmmmm very curious indeed.
Funny you should post this SweatM as I was thinking of a way to use some HCG in small amounts to reap the benefit if any other than HPTA restoration.

The older I get the more I think how much supraphysiological doses of any substance is NOT required for beneficial results.

So far GH, T3, and Test used this way has not disappointed.

I love these types of posts because they are backed with real world experiences rather than volumes of technical jargon. I don't think we will really have a true explanation as how this exactly works but there were some good responses by Sweat and and an awesome post by homonunculus.
Personally my experience with HCG has been negative to say the least in semi large doses.
In the past when used with semi moderate doses it does reset the HPTA but appears to give me another crash a few weeks after use of 5-1000 iu's EOD.

Also HCG is the only thing that appears to begin to give me gyno..itchy nips and soreness that do eventually go away.

It was a secret weapon in a contest stack for some bb'ers I don't really know why but some did use it this way in the 80's and 90's and some may still do.
One guy I competed against in the early 1990's used it to get some serious conditoning.
Hell he almost beat me he looked smooth and big 2 weeks before the show and added HCG in and boom he was ripped hard and lean and tight the day of the show. (He claimed it weas the HCG-laughing at me since I gave it to him)
So there may be a lil something something behind the fat and water loss idea.

Interesting to say the least as HCG to me was primary a use for HPTA restoration.
I may try this vey shortly and post results.
Thanks again for sharing the info in this post it really gets one thinking! :Phone:

[massxpress]

I know that HCG is a weak "thyrotropic" hormone. So, it will have thyroid stimulating properties. There is a part of HCG that is identical to TSH(the alpha part, if I remember correctly) That's why in the 1st trimester of pregnant woman have an increase in free thyroxine levels and decrease TSH(supression). This is transient, but with the levels that are being mentioned maybe there is a greater increase in t4 and t3. I mean I am just guessing because so much more goes on with an increase in hcG during pregnancy(changes in TBG, estrogen,etc.) hcG definitely increases t4 and some t3, the bodybuilder injecting hcG at higher levels might illicit a response much like that of the pregnant woman, so I do think it can be used in fat loss. Again, This is a bbing answer to a bbing question, so much goes on with the increase in hcG.

[homonunculus]

I know that HCG is a weak "thyrotropic" hormone. So, it will have thyroid stimulating properties. There is a part of HCG that is identical to TSH(the alpha part, if I remember correctly) That's why in the 1st trimester of pregnant woman have an increase in free thyroxine levels and decrease TSH(supression). This is transient, but with the levels that are being mentioned maybe there is a greater increase in t4 and t3. I mean I am just guessing because so much more goes on with an increase in hcG during pregnancy(changes in TBG, estrogen,etc.) hcG definitely increases t4 and some t3, the bodybuilder injecting hcG at higher levels might illicit a response much like that of the pregnant woman, so I do think it can be used in fat loss. Again, This is a bbing answer to a bbing question, so much goes on with the increase in hcG.

I like this idea MUCH better than mine (although they are all related, leptin also stimulate thyroxine output).

This is pretty cool, if you look at it.

Leptin inhibits TSH release from the pituitary but stimulates thyroid production from the thyroid itself - it has a regulatory role.

HCG would, due to this sequence homology you mentioned, mass, stimulate TSH release.

The question still remains as to what HCG is doing to leptin. If HCG reduces leptin, then the there is less inhibition (less leptin) and more stimulation (HCG) of TSH release. The TSH would / could (?) have a stronger influence on thyroid output than reducing leptin: metabolic rate is increased.

If HCG increases leptin, it stimulates thyroid output at the thyroid (via leptin) and may counterbalance the inhibitor effect of leptin on TSH b/c of its (HCG's) TSH-like effects.

Basically - I still don't know what the hell I'm talkin' about... LOL.

It would VERY COOL to get thyroid panel done before and during a low dose HCG protocol to see what's up with TSH, T3, etc...

Great post, mass!

-R